Anand Swaroop Selected Research

Retinitis Pigmentosa (Pigmentary Retinopathy)

7/2017	EYS Mutations Causing Autosomal Recessive Retinitis Pigmentosa: Changes of Retinal Structure and Function with Disease Progression.
1/2017	Transcriptome profiling of NIH3T3 cell lines expressing opsin and the P23H opsin mutant identifies candidate drugs for the treatment of retinitis pigmentosa.
5/2016	Loss of RPGR glutamylation underlies the pathogenic mechanism of retinal dystrophy caused by TTLL5 mutations.
3/2016	Genetic Analysis of the Rhodopsin Gene Identifies a Mosaic Dominant Retinitis Pigmentosa Mutation in a Healthy Individual.
7/2015	A long-term efficacy study of gene replacement therapy for RPGR-associated retinal degeneration.
6/2013	Developing rods transplanted into the degenerating retina of Crx-knockout mice exhibit neural activity similar to native photoreceptors.
12/2012	Mutations in RPGR and RP2 account for 15% of males with simplex retinal degenerative disease.
8/2012	RPGR-associated retinal degeneration in human X-linked RP and a murine model.
2/2012	Gene therapy rescues photoreceptor blindness in dogs and paves the way for treating human X-linked retinitis pigmentosa.
1/2012	Rd9 is a naturally occurring mouse model of a common form of retinitis pigmentosa caused by mutations in RPGR-ORF15.

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Anand Swaroop Research Topics

Disease

32	Macular Degeneration (Age-Related Maculopathy) 01/2021 - 08/2002
29	Retinitis Pigmentosa (Pigmentary Retinopathy) 07/2017 - 01/2003
21	Retinal Degeneration 10/2020 - 01/2003
15	Retinal Diseases 07/2019 - 03/2002
12	Ciliopathies 01/2021 - 02/2008
11	Leber Congenital Amaurosis 01/2021 - 01/2003
7	Blindness (Hysterical Blindness) 01/2020 - 07/2005
6	Eye Diseases (Eye Disease) 05/2021 - 11/2014
6	Disease Progression 01/2018 - 12/2011
5	Inflammation (Inflammations) 01/2018 - 06/2005
5	Cone-Rod Dystrophies 11/2016 - 07/2007
4	Insulin Resistance 05/2018 - 10/2015
4	Neurodegenerative Diseases (Neurodegenerative Disease) 11/2015 - 03/2007
3	Microphthalmos 09/2021 - 04/2012
3	Diabetic Retinopathy (Retinopathy, Diabetic) 11/2020 - 01/2012
3	Atrophy 09/2019 - 10/2002
3	Agenesis of Cerebellar Vermis 11/2017 - 06/2006
3	Body Weight (Weight, Body) 09/2017 - 01/2015
3	Hydrocephalus (Hydrocephaly) 01/2012 - 01/2010
3	Retinal Dystrophies 01/2012 - 10/2007
2	Ganglion Cysts (Ganglion) 09/2021 - 09/2004
2	Hypoxia (Hypoxemia) 01/2020 - 01/2016
2	Geographic Atrophy 08/2019 - 01/2018
2	Metabolic Syndrome (Dysmetabolic Syndrome X) 05/2018 - 09/2017
2	Hypertension (High Blood Pressure) 11/2017 - 12/2005
2	Sensorineural Hearing Loss 11/2016 - 01/2016
2	Coloboma (Colobomas) 04/2016 - 04/2012
2	Retinitis Pigmentosa 2 11/2015 - 07/2013
2	Retinal Detachment (Retinal Detachments) 01/2012 - 04/2006
2	Cysts 11/2010 - 06/2006
2	Senior Loken Syndrome 12/2009 - 03/2005
2	Enhanced S-Cone Syndrome 10/2009 - 01/2003
2	Retinoblastoma (Glioblastoma, Retinal) 04/2008 - 09/2006
2	Leukemia 11/2007 - 12/2006
2	Atherosclerosis 12/2005 - 06/2005
1	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 11/2020
1	Optic Nerve Diseases (Optic Neuropathy) 01/2020
1	Cognitive Dysfunction 01/2020
1	Autosomal Dominant Optic Atrophy (Dominant Optic Atrophy) 01/2020
1	Infertility (Sterility) 01/2020
1	Familial Hypoadrenocorticism 09/2019
1	Cohen syndrome 09/2019
1	Ichthyosis (Xeroderma) 09/2019
1	Sjogren-Larsson Syndrome 09/2019
1	Ophthalmoplegia (External Ophthalmoplegia) 09/2019
1	Degenerative Myopia 09/2019
1	Mucopolysaccharidosis I (Hurler Syndrome) 10/2018
1	Dyslipidemias (Dyslipidemia) 01/2018
1	Non-alcoholic Fatty Liver Disease 01/2018
1	Hemorrhage 01/2018

Drug/Important Bio-Agent (IBA)

45	Retinaldehyde (Retinal)IBA 09/2021 - 08/2002
28	Proteins (Proteins, Gene)FDA Link 01/2020 - 03/2002
14	GTP Phosphohydrolases (GTPases)IBA 05/2016 - 03/2005
6	Glucose (Dextrose)FDA LinkGeneric 11/2020 - 01/2012
6	Complement Factor H (Factor H)IBA 11/2019 - 07/2005
5	Complement System Proteins (Complement)IBA 01/2019 - 04/2008
4	Transcription Factors (Transcription Factor)IBA 01/2021 - 01/2003
4	Rhodopsin (Visual Purple)IBA 10/2020 - 10/2002
4	Apolipoproteins E (ApoE)IBA 12/2011 - 05/2004
4	Protein Isoforms (Isoforms)IBA 06/2011 - 06/2007
3	Carrier Proteins (Binding Protein)IBA 01/2020 - 09/2005
3	C-Reactive ProteinIBA 05/2018 - 12/2005
3	Pharmaceutical PreparationsIBA 01/2016 - 10/2014
3	MorpholinosIBA 01/2012 - 01/2010
2	Biological ProductsIBA 01/2021 - 12/2012
2	Mitochondrial DNA (mtDNA)IBA 01/2020 - 01/2016
2	Triglycerides (Triacylglycerol)IBA 05/2018 - 09/2017
2	Alanine Transaminase (SGPT)IBA 01/2018 - 09/2017
2	Insulin (Novolin)FDA Link 01/2018 - 09/2017
2	Aspartate Aminotransferases (Aspartate Transaminase)IBA 01/2018 - 09/2017
2	SugarsIBA 11/2017 - 01/2016
2	HDL LipoproteinsIBA 09/2017 - 04/2010
2	OpsinsIBA 01/2017 - 07/2013
2	Mutant Proteins (Protein, Mutant)IBA 04/2016 - 06/2010
2	SaponinsIBA 01/2016 - 10/2015
2	fenugreek seed mealIBA 01/2016 - 01/2015
2	RNA (Ribonucleic Acid)IBA 01/2012 - 04/2008
2	Type I DNA Topoisomerases (Topoisomerase I)IBA 03/2011 - 11/2007
1	Glycogen Synthase Kinase 3IBA 09/2021
1	polycaprolactoneIBA 01/2020
1	PolymersIBA 01/2020
1	NADH DehydrogenaseIBA 01/2020
1	Oxidants (Oxidizing Agents)IBA 01/2020
1	ZincIBA 11/2019
1	LuteinIBA 11/2019
1	Carotenoids (Carotene)IBA 11/2019
1	Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA 11/2019
1	ZeaxanthinsIBA 11/2019
1	Nonsense Codon (Nonsense Mutation)IBA 09/2019
1	Iduronidase (alpha-L-Iduronidase)IBA 10/2018
1	GlycosaminoglycansIBA 10/2018
1	EnzymesIBA 10/2018
1	Blood Glucose (Blood Sugar)IBA 05/2018
1	Transaminases (Aminotransferases)IBA 01/2018
1	Retinal Pigments (Pigments, Visual)IBA 01/2018
1	SaltsIBA 11/2017

Therapy/Procedure

16	Therapeutics 05/2021 - 11/2007
2	Mediterranean Diet 11/2020 - 01/2020
1	Bioreactors (Bioreactor) 01/2018
1	Precision Medicine 12/2017